Synonym:
Spectinomycin
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EC Number 244-554-3
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MDL number MFCD04041129
Properties:
| Related Categories |
Additional Standards,
Analytical Standards,
Analytical/Chromatography,
Chromatography,
Pharmaceutical Secondary Standards,
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grade
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certified reference material
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pharmaceutical secondary standard
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description
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Pharmaceutical Secondary Standard; Certified Reference Material
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packaging
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pkg of 500 mg
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pharmacopeia traceability
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traceable to PhEur Y0000597
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traceable to USP 1618003
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Description:
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Biochem/physiol Actions
Mode of Action: Spectinomycin acts by inhibiting protein synthesis and elongation by binding to the bacterial 30S ribosomal subunit and interfering with peptidyl tRNA translocation.
Mode of Resistance: A mutation in rpsE, the gene for ribosomal protein S5, prevents the binding of spectinomycin. Resistance is also conferred by the aminoglycoside-3′-adenyltransferase gene (aadA).
Antimicrobial spectrum: Spectinomycin acts against gram-negative and gram-positive bacteria.
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards
Other Notes
This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA2734 in the slot below. This is an example certificate only and may not be the lot that you receive.
Safety:
RIDADR
NONH for all modes of transport
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4000-520-616
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