Synonym:
(2-Hydroxypropyl)-beta-cyclodextrin
Properties:
| Related Categories |
Analytical Reagents,
Analytical/Chromatography,
Capillary Electrophoresis,
Chelation/Complexation Compounds,
Chemical Synthesis,
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optical activity
|
[α]26/D +139°, c = 1 in H2O
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mol wt
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average Mw ~1,380
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extent of labeling
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0.6 molar substitution
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|
mp
|
278 °C (dec.)
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Description:
Application
The solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice.
Packaging
1 kg in poly drum
5, 25, 100 g in poly bottle
Safety:
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR
NONH for all modes of transport